Two Case Reports of Pilot Percutaneous Cryosurgery in Familial Multiple Endocrine Neoplasia Type 1

Since the first case report of multiple endocrine tumors in 1903 by Erdheim, the definition of this disease has been debated. In 1968, Steiner introduced the term multiple endocrine neoplasia (MEN) to describe disorders that featured combinations of endocrine tumors. This disease was then divided intoWermer syndrome (MEN 1) and Sipple syndrome (MEN 2).